RICHARD L. KLEIN, M.D.; JOHN A. MCCHESNEY
Since the classic experiments of Goldblatt,1 interest in the renal origin of hypertension has increased greatly, in part because hypertension occurring in association with unilateral renal disease is potentially curable by removal of the involved organ. Unilateral renal arterial disease, though less commonly associated with hypertension than is unilateral pyelonephritis, has been associated with a much higher rate of cured hypertension following nephrectomy. The general opinion, as reflected by Thompson and Smithwick,2 is that renal arterial lesions represent the closest clinical counterpart to the experimental Goldblatt kidney.
Characteristically, patients with renal arterial disease have an abrupt onset of hypertension. Flank
KLEIN RL, MCCHESNEY JA. HYPERTENSION SECONDARY TO ANEURYSM OF THE RENAL ARTERY: REPORT OF A CASE OF LONG DURATION CURED BY NEPHRECTOMY1. Ann Intern Med. 1961;54:292–300. doi: 10.7326/0003-4819-54-2-292
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Published: Ann Intern Med. 1961;54(2):292-300.
Cardiology, Coronary Risk Factors, Hypertension, Nephrology.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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