FEDERICO DÍES, M.D.; SERGIO RANGEL, M.D.; ALFONSO RIVERA, M.D., M.SC.
Diabetes insipidus is defined as the disease in which antidiuretic hormone (ADH) is not produced even in the presence of an appropriate stimulus. As a result, the patient passes large volumes of a hypotonic urine. There is also the disease, nephrogenic diabetes insipidus, in which sufficient amounts of ADH are produced, but the collecting tubules of the nephrons are insensitive to its action. On the other hand, clinical disturbances have been described in which the hypothalamic center of thirst is persistently affected and thirst sensation disappears or increases.1 In the case of hyperdipsia, the increased water intake inhibits the release
DÍES F, RANGEL S, RIVERA A. DIFFERENTIAL DIAGNOSIS BETWEEN DIABETES INSIPIDUS AND COMPULSIVE POLYDIPSIA1. Ann Intern Med. ;54:710–725. doi: 10.7326/0003-4819-54-4-710
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Published: Ann Intern Med. 1961;54(4):710-725.
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