RICHARD WEDEEN, M.D.
The differential diagnosis of polyuria and polydipsia is a common problem. Increased renal water loss may occur with: (1) diabetes mellitus, (2) chronic nephritis, (3) severe thyrotoxicosis, (4) kaliopenic nephropathy, (5) hypercalcemia, (6) diabetes insipidus, both primary and nephrogenic, and (7) psychogenic polydipsia. The first five of this group can be differentiated by specific laboratory and clinical studies. There remains, however, the frequently encountered problem of distinguishing primary diabetes insipidus from nephrogenic insipidus and from psychogenic polydipsia.
The case herein reported is an example of prolonged functional depression of antidiuretic mechanisms secondary to excessive water intake and simulating primary diabetes
WEDEEN R. PROLONGED FUNCTIONAL DEPRESSION OF ANTIDIURETIC MECHANISMS IN PSYCHOGENIC POLYDIPSIA SIMULATING PRIMARY DIABETES INSIPIDUS1. Ann Intern Med. ;54:805–809. doi: 10.7326/0003-4819-54-4-805
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Published: Ann Intern Med. 1961;54(4):805-809.
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