T. N. James, M.D., (Assoc.)
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Syncope and sudden death are common clinical features of primary pulmonary hypertension. A number of hypotheses have been proposed to explain these phenomena but none has been fully satisfactory. One discrepancy has been the uncommon appearance of these features in secondary pulmonary hypertension.
While studying the histopathology of the sinus node and its artery in a variety of diseases, a case of primary pulmonary hypertension was examined. The sinus node in this case was extensively infarcted. The sinus node artery was not only ruptured, but the media in all areas showed degeneration, both cystic and noncystic. More careful examination of
James TN. On the Cause of Syncope and Sudden Death in Primary Pulmonary Hypertension.. Ann Intern Med. 1961;54:1034–1035. doi: 10.7326/0003-4819-54-5-1034_3
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Published: Ann Intern Med. 1961;54(5):1034-1035.
Neurology, Pulmonary Hypertension, Pulmonary/Critical Care.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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