J. V. Messer, M.D.; W. A. Neill, M.D.; R. J. Wagman, M.D.; H. J. Levine, M.D.; R. Gorlin, M.D., (Assoc.)
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Myocardial oxygen requirements (MqO2) are supplied by the interaction of coronary blood flow (CBF) and myocardial oxygen extraction. Earlier studies have shown the relative constancy of myocardial O2 extraction in various states (rest, exercise, hypoxia, anemia), so long as coronary blood flow reserve is unimpaired.
Forty-four patients were studied by coronary venous catheterization at rest and during exercise with measurement of coronary and systemic hemodynamics. Distinct patterns of myocardial O2 supply were observed in various clinical states. In 22 normals the increased MqO2 of exercise was supplied by increased CBF and resting levels of O2 extraction (70%). In seven coronary
Messer JV, Neill WA, Wagman RJ, Levine HJ, Gorlin R. Physiologic Evaluation of the Coronary Circulation in Coronary Disease and in Congestive Failure.. Ann Intern Med. ;54:1037–1038. doi: 10.7326/0003-4819-54-5-1037_2
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Published: Ann Intern Med. 1961;54(5):1037-1038.
Cardiology, Coronary Heart Disease.
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