T. Rodman, M.D., (Assoc.); C. A. Gorczyca, M.D.; B. H. Pastor, M.D., F.A.C.P.
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Although it is generally stated that digitalis reduces the cardiac output of the normal heart, the experimental basis for the statement is questionable. The available data are sparse and contradictory because, until recently, determinations of the cardiac output required catheterization of the pulmonary artery and application of the Fick principle, a technically difficult and time-consuming procedure which is not readily reproducible.
A study was therefore undertaken utilizing a highly standardized dye dilution technic for the measurement of cardiac output. Sixteen normal young adult men were studied. The cardiac output, heart rate, stroke volume, minute ventilation, oxygen uptake, CO2 production, and
T. Rodman, C. A. Gorczyca, B. H. Pastor. The Effect of Digitalis on the Cardiac Output of the Normal Heart at Rest and During Exercise.. Ann Intern Med. 1961;54:1039–1040. doi: 10.7326/0003-4819-54-5-1039_3
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Published: Ann Intern Med. 1961;54(5):1039-1040.
Cardiac Diagnosis and Imaging, Cardiology.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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