L. E. Hollister, M.D., F.A.C.P.; W. L. Arons, M. D., (Assoc.)
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Both of the naturally-occurring thyroid hormones, 1-thyroxine and 1-tri-iodothyronine, have been found to lower serum cholesterol levels in euthyroid and hypothyroid hypercholesterolemic subjects. The effects of the dextro-isomers, especially d-tri-iodothyronine, on serum lipids will be presented in this paper. Eleven euthyroid patients with elevated serum cholesterol levels have been treated with d-tri-iodothyronine for one year with doses of from 0.2 to 1.5 mg. per day. The minimal effective dose was 0.2 mg./day, which decreased serum cholesterol by 23% in one patient. Four patients experienced decreases of from 21 to 26% on doses of 0.4 mg. daily. Four patients required doses
Hollister LE, Arons WL. Effect of Dextro-Isomers of Thyroid Hormones on Serum Cholesterol Levels in Euthyroid Hypercholesterolemic Patients.. Ann Intern Med. ;54:1045. doi: 10.7326/0003-4819-54-5-1045_1
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Published: Ann Intern Med. 1961;54(5):1045.
Cardiology, Coronary Risk Factors, Dyslipidemia.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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