F. G. Ebaugh Jr., M.D., F.A.C.P.; W. Beeken, M.D.
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Previous work in this laboratory has shown by a chemical photospectrometric technic that the normal 24-hr. fecal blood loss is 1.70 ± 1.2 ml., and is not influenced by diet or iron therapy. Utilizing this chemical quantitative test, it was found that the qualitative benzidine-2HCL test on three serial stool samples gives 50% false positive and 2% false negative results. Less than 6% of false positive qualitative tests are caused by concentration of the 24-hr. stool volume or by unequal distribution of blood in the stool. Fifty per cent of patients with gastrointestinal malignancies show normal 24-hr. quantitative fecal blood
Ebaugh FG, Beeken W. Comparative Usefulness of Qualitative and Quantitative Stool Occult Blood Tests in the Diagnosis of Gastrointestinal Disease.. Ann Intern Med. ;54:1048. doi: 10.7326/0003-4819-54-5-1048_1
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Published: Ann Intern Med. 1961;54(5):1048.
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