G. L. Baum, M.D., F.A.C.P.; D. Artis, B.S.
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Previous work has shown that cell-free human serum is bacteriostatic and in some instances bactericidal. This has been a nonspecific effect and not related to previous immunization. The present study was done with several species of pathogenic fungi and with species that are only occasionally pathogenic for humans.
Cryptococcus neoformans, Sporotrichum schenckii, Candida albicans, Penicillium species and Aspergillus species were tested for inhibition by cell-free human serum obtained by the usual method of venipuncture and frozen until the experiments were set up. Physicians and patients were sources of serum. Both individual and pooled sources were used.
Culture tubes were filled
Baum GL, Artis D. Fungistatic Effects of Cell-Free Human Serum.. Ann Intern Med. ;54:1053. doi: 10.7326/0003-4819-54-5-1053_1
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Published: Ann Intern Med. 1961;54(5):1053.
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