RUSSELL E. RANDALL JR.; WILLIAM H. TARGGART, M.D.
Acidosis of renal origin is an increased hydrogen ion concentration due to an impairment in the excretion of titratable acid and/or ammonium ion, to an excessive excretion of bicarbonate, or to a combination of these two defects.1-4 While all renal acidosis is presumably tubular in origin, the term "renal tubular acidosis" has come to represent (and will be so used in this text) that syndrome characterized by a hyperchloremic acidosis resulting from marked impairment in the ability to excrete an acid urine.3-15 The latter is significantly out of proportion to any impairment in glomerular filtration, and hence is not associated
RUSSELL E. RANDALL, WILLIAM H. TARGGART. FAMILIAL RENAL TUBULAR ACIDOSIS(FAMILIAL RENAL TUBULAR ACIDOSIS*). Ann Intern Med. 1961;54:1108–1116. doi: 10.7326/0003-4819-54-6-1108
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Published: Ann Intern Med. 1961;54(6):1108-1116.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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