MONROE THOMAS DIAMOND, M.D., F.A.C.P.
It has long been noted that disorders of the nervous system can occur in association with malignancy and yet be unrelated to the presence of metastases. As far back as 1888 Oppenheim1 reported the occurrence of peripheral neuritis in malignant disease, and suggested that this was the result of a toxic process. Nonne2 in 1900 and Siefert3 in 1902 supported this view. In 1908 Williamson4 stated that posterior column degeneration had been seen in cases of cachexia associated with cancer of various organs, and in 1919 subacute cortical cerebellar degeneration was described in association with neoplasms by Brouwer5 and Jelgersma.6
DIAMOND MT. CARCINOMATOUS NEUROPATHY1. Ann Intern Med. ;54:1259–1266. doi: 10.7326/0003-4819-54-6-1259
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Published: Ann Intern Med. 1961;54(6):1259-1266.
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