LORNE D. FELDMAN, M.D.
To the editor: Breast cancer accounts for more than 25% of malignancies in women but less than 0. 2% of malignancies in men (1). Compared to women, men are generally older and have a more advanced stage of breast cancer at diagnosis. The presentation in them frequently includes a periareolar breast mass, ulcerative abnormalities of the nipple, invasion of the pectoralis muscle, and involvement of the axillary lymph node. Radical mastectomy is the usual approach to control the primary neoplasm. Distant metastatic sites are similar to those seen in women. The frequency of estrogen- and progesterone-receptor positivity is higher in
FELDMAN LD. Ketoconazole for Male Metastatic Breast Cancer. Ann Intern Med. 1986;104:123–124. doi: 10.7326/0003-4819-104-1-123_2
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Published: Ann Intern Med. 1986;104(1):123-124.
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