ALICIA DE MEDINA, M.D.; OLIVIA BIASINI, M.D.; ALFONSO RIVERA, M.D.; ALICIA SAMPERA, M.D.
To the editor: Hicks and Abraham (1) have reported a case of myoclonic dystonia associated with verapamil therapy. We report the case of a patient who developed myoclonic dystonia apparently induced by nifedipine, a calcium-ion-influx inhibitor. Although nifedipine has side effects (2), such as headache, flushing, lethargy, dizziness, allergic reactions, hypotension, palpitations, and sometimes anginal pain, they are mainly transient.
A 35-year-old man was hospitalized with status asthmaticus. He was receiving oxytriphylline (Choledyl; Parke-Davis, Morris Plains, New Jersey), 600 mg/d, and prednisone, 15 mg/d. Three days after admission, we started him on nifedipine therapy, because some studies have reported that
DE MEDINA A, BIASINI O, RIVERA A, SAMPERA A. Nifedipine and Myoclonic Dystonia. Ann Intern Med. ;104:125. doi: 10.7326/0003-4819-104-1-125_2
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Published: Ann Intern Med. 1986;104(1):125.
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