STEVEN A. TEICH, M.D.; JUAN ORELLANA, M.D.
To the editor: A recent article by Felsenstein and colleagues (1) concerns the treatment of cytomegalovirus retinitis with 9-[2-hydroxy-1-(hydroxymethyl)ethoxymethyl]guanine. We have also been using this drug to treat cytomegalovirus retinitis in patients with the acquired immunodeficiency syndrome (AIDS) and concur that many patients have clinical improvement with healing of retinal lesions but that recurrence is virtually universal within a few weeks of stopping therapy.
We do, however, disagree with the description of the fundus in these patients for documenting cytomegalovirus retinitis. Patient 1 was described as having "nerve infarcts, compatible with cytomegalovirus retinitis." In fact, nerve infarcts or cotton-wool spots
TEICH SA, ORELLANA J. Retinal Lesions in Cytomegalovirus Infection. Ann Intern Med. ;104:132. doi: 10.7326/0003-4819-104-1-132_2
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Published: Ann Intern Med. 1986;104(1):132.
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