ROBERT D. INMAN, M.D.
To the editor: In the March issue, Dr. Popp and colleagues (1) reported their observations on the occurrence of hepatitis B infection in essential mixed cryoglobulinemia. Their finding that only one of 10 cryoprecipitates contained either HBsAg or anti-HBs is at odds with the earlier report of Levo and associates (2) that 14 of 19 cryoprecipitates from patients with essential mixed cryoglobulinemia had either HBsAg or anti-HBs. It is difficult to assess whether this variance represents differences in the prevalence of hepatitis B infection in the communities because the control groups differ. Popp and coworkers included secondary mixed cryoglobulinemia (finding
INMAN RD. Hepatitis B Infection and Mixed Cryoglobulinemia. Ann Intern Med. ;93:377. doi: 10.7326/0003-4819-93-2-377_1
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Published: Ann Intern Med. 1980;93(2):377.
Gastroenterology/Hepatology, Infectious Disease, Liver Disease, Viral Hepatitis.
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