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Letters |5 March 2013

Antipsychotics in Adults With Schizophrenia: Does Sponsorship of Research Articles Affect the Findings?

Thomas E. Finucane, MD

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Author, Article, and Disclosure Information
  • From Johns Hopkins Bayview Medical Center, Baltimore, Maryland.

    Potential Conflicts of Interest: None disclosed.

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TO THE EDITOR:
As suggested in Hartling and colleagues' review comparing first-generation with second-generation antipsychotics (1) and shown in other contexts, the sponsorship of research articles may affect the findings. Can the authors say anything about the effects of pharmaceutical sponsorship on the outcomes of the trials that they reviewed? They note that chance of bias was substantial in many of the studies, and funding was not disclosed in 19% of articles (1). Corrupt research might be a particular problem with these vendors, as they have been paying billions of dollars in fines recently for a variety of behaviors related to promoting their products.
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Finucane TE. Antipsychotics in Adults With Schizophrenia: Does Sponsorship of Research Articles Affect the Findings?. Ann Intern Med. ;158:362. doi: 10.7326/0003-4819-158-5-201303050-00014

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Published: Ann Intern Med. 2013;158(5_Part_1):362.

DOI: 10.7326/0003-4819-158-5-201303050-00014

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Print ISSN: 0003-4819 | Online ISSN: 1539-3704

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