Skip Navigation
Menu
ACP Journal Club |15 April 2014

Review: Nicotine replacement therapy increases CVD events; bupropion and varenicline do not

Kate Rowland, MD, MS

Article, Author, and Disclosure Information
FULL TEXT
Mills EJ, Thorlund K, Eapen S, Wu P, Prochaska JJ. Cardiovascular events associated with smoking cessation pharmacotherapies: a network meta-analysis. Circulation. 2014;129:28-41. 24323793

GIM/FP/GP:

Image: rating_5.png

Mental Health:

Image: rating_6.png

Cardiology:

Image: rating_5.png

Do smoking cessation therapies (nicotine replacement therapy [NRT], bupropion, and varenicline) increase risk for cardiovascular (CV) events?
Included studies assessed NRT (any marketed dose or combination) or licensed doses of bupropion or varenicline for any duration as cessation therapy in smokers and reported CVD events. Outcomes were any CV event and major adverse CV events (MACE) (CV death, nonfatal myocardial infarction, and nonfatal stroke).
FULL TEXT
PDF
Not Available
Citations
Citation

Rowland K. Review: Nicotine replacement therapy increases CVD events; bupropion and varenicline do not. Ann Intern Med. 2014;160:JC2. doi: 10.7326/0003-4819-160-8-201404150-02002

Download citation file:

© 2018

×
Permissions

Published: Ann Intern Med. 2014;160(8):JC2.

DOI: 10.7326/0003-4819-160-8-201404150-02002

0 Citations

Related Articles
In smokers with COPD, neither varenicline nor bupropion was linked to increased CV or neuropsychiatric risk vs NRT
Annals of Internal Medicine; 167 (6): JC31
Review: Varenicline is better than bupropion but not nicotine patch for smoking abstinence in adults
Annals of Internal Medicine; 157 (6): JC3-7
Review: Varenicline is better than placebo or bupropion, but not clearly different from the nicotine patch, for smoking abstinence
Annals of Internal Medicine; 154 (8): JC4-4
Exploring the Geometry of Treatment Networks
Annals of Internal Medicine; 148 (7): 544-553
View MoreView Less

Journal Club
In smokers with COPD, neither varenicline nor bupropion was linked to increased CV or neuropsychiatric risk vs NRT
Annals of Internal Medicine; 167 (6): JC31
Review: Varenicline is better than bupropion but not nicotine patch for smoking abstinence in adults
Annals of Internal Medicine; 157 (6): JC3-7
Review: Varenicline is better than placebo or bupropion, but not clearly different from the nicotine patch, for smoking abstinence
Annals of Internal Medicine; 154 (8): JC4-4
In stable CVD, rivaroxaban plus aspirin reduced CV events and increased bleeding compared with aspirin alone
Annals of Internal Medicine; 167 (10): JC52
View MoreView Less

Related Point of Care
Smoking Cessation
Annals of Internal Medicine; 164 (5): ITC33-ITC48
View MoreView Less

Related Topics
Cardiology
Coronary Risk Factors
Smoking
Tobacco, Alcohol, and Other Substance Abuse

Cardiology, Coronary Risk Factors, Smoking, Tobacco, Alcohol, and Other Substance Abuse.

PubMed Articles
Phenotypic characteristics of the p.Asn215Ser (p.N215S) GLA mutation in male and female patients with Fabry disease: A multicenter Fabry Registry study.
Mol Genet Genomic Med 2018.
Patent Foramen Ovale and Cryptogenic Stroke or Transient Ischemic Attack: To Close or Not to Close? A Systematic Review and Meta-Analysis.
Cerebrovasc Dis 2018;
View More

Results provided by: PubMed

CONTINUE WITH LIMITED ACCESS
Annals of Internal Medicine
To receive access to the full text of freely available articles, alerts, and more. You will be directed to acponline.org to complete your registration.
×
acp link acp
silverchair link silverchair

Copyright © 2018 American College of Physicians. All Rights Reserved.

Print ISSN: 0003-4819 | Online ISSN: 1539-3704

Privacy Policy

|

Conditions of Use

×

You need a subscription to this content to use this feature.

×
PDF Downloads Require Access to the Full Article.
Annals of Internal Medicine
To receive access to the full text of freely available articles, alerts, and more. You will be directed to acponline.org to complete your registration.
×
Access to this Free Content Requires Users to be Registered and Logged In. Please Choose One of the Following Options
Annals of Internal Medicine
To receive access to the full text of freely available articles, alerts, and more. You will be directed to acponline.org to complete your registration.
×