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Updates |5 May 2015

Update in Endocrinology: Evidence Published in 2014

Jennifer B. Green, MD

Article, Author, and Disclosure Information
Author, Article, and Disclosure Information
This article was published online first at www.annals.org on 30 April 2015.
  • From Duke University Medical Center, Durham, North Carolina.

    Disclosures: Disclosures can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=M15-0153.

    Request for Single Reprints: Jennifer B. Green, MD, Division of Endocrinology, Duke University Medical Center, DUMC Box 3850, 2400 Pratt Street, Room 7039, North Pavilion, Durham, NC 27705; e-mail, green094@mc.duke.edu.

    Author Contributions: Conception and design: J.B. Green.

    Analysis and interpretation of the data: J.B. Green.

    Drafting of the article: J.B. Green.

    Critical revision of the article for important intellectual content: J.B. Green.

    Final approval of the article: J.B. Green.

    Statistical expertise: J.B. Green.

    Collection and assembly of data: J.B. Green.

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FULL TEXT
This update summarizes 8 articles published in 2014 that significantly advanced our understanding of an endocrine-related condition. Publications were identified from core clinical journals by searching PubMed and ACP JournalWise for keywords related to major subspecialty areas within endocrinology. Selected articles addressed prevalent conditions of public health importance and were judged likely to appeal to a broad audience and have findings pertinent to safety and value of care.
The studies chosen that are relevant to diabetes and obesity present a new lifestyle option for diabetes prevention; alert us to commonly used drug combinations that increase hypoglycemia risk; and review the role of bariatric surgery in diabetes remission and prevention of diabetes-related complications. Results from the HPS2-THRIVE (Heart Protection Study 2–Treatment of HDL to Reduce the Incidence of Vascular Events) trial define the efficacy and safety of adding extended-release niacin to statin therapy for secondary prevention of cardiovascular events. Two systematic reviews scrutinize data on the utility of vitamin D supplementation and pharmacologic therapies in osteoporotic fracture prevention. A new analysis of corticosteroid use in patients with septic shock should prompt further study of this practice, whereas a comprehensive analysis of population data on thyroid cancer raises important questions concerning current management strategies for thyroid nodules.
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Green JB. Update in Endocrinology: Evidence Published in 2014. Ann Intern Med. ;162:W91–W95. doi: 10.7326/M15-0153

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Published: Ann Intern Med. 2015;162(9):W91-W95.

DOI: 10.7326/M15-0153

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