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Letters |19 May 2015

Effect of Ebola Progression in Liberia

Prasanta Raghab Mohapatra, MD; Baijayantimala Mishra, MD

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TO THE EDITOR:
Yamin and colleagues (1) evaluated the probability of eliminating Ebola by case isolation of 50% to 100% of nonsurvivors compared with isolation of all infected persons when the type of contact is dominated by conversation or by sharing a meal or a bed. However, they do not mention the transmission of the virus during conversation, or aerosol transmission. Masks are protective only when they are of good quality and properly used.
Filoviruses are classified as category A bioterrorism agents by the Centers for Disease Control and Prevention and are thought to be aerosol-mediated. Countering aerosolized filovirus infection has been a major priority of biodefense research (2). Transmission of Marburg virus by exposure to bat-inhabited caves and mines has already been reported (3). In a study by Reed and associates, when cynomolgus and rhesus macaques and African green monkeys were exposed to aerosolized Zaire ebolavirus, all 3 species developed similar clinical signs and symptoms and the outcome resembled that of parenteral inoculation with the virus for each species (4).
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Mohapatra PR, Mishra B. Effect of Ebola Progression in Liberia. Ann Intern Med. 2015;162:734. doi: 10.7326/L15-5092

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Published: Ann Intern Med. 2015;162(10):734.

DOI: 10.7326/L15-5092

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