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ACP Journal Club |20 June 2017

In adults at risk for contrast-induced nephropathy, no prophylactic hydration was noninferior to hydration

Brent Wagner, MD, FACP, FASN

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Nijssen EC, Rennenberg RJ, Nelemans PJ, et al. Prophylactic hydration to protect renal function from intravascular iodinated contrast material in patients at high risk of contrast-induced nephropathy (AMACING): a prospective, randomised, phase 3, controlled, open-label, non-inferiority trial. Lancet. 2017;389:1312-22. 28233565

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In adults at risk for contrast-induced nephropathy (CIN), is no prophylactic hydration noninferior to guideline-based, standard prophylactic hydration for preventing CIN?
Randomized controlled trial (A MAstricht Contrast-Induced Nephropathy Guideline [AMACING] trial). ClinicalTrials.gov NCT02106234.
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Wagner B. In adults at risk for contrast-induced nephropathy, no prophylactic hydration was noninferior to hydration. Ann Intern Med. ;166:JC66. doi: 10.7326/ACPJC-2017-166-12-066

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Published: Ann Intern Med. 2017;166(12):JC66.

DOI: 10.7326/ACPJC-2017-166-12-066

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2017 American College of Physicians
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