MAURICE SOKOLOW, M.D.; FRANCIS L. CHAMBERLAIN, M.D.
The pure glycosides of digitalis have been the subject of many recent pharmacological and clinical investigations. Originally all the studies were purely chemical, but they have assumed clinical importance. The crude whole leaf of Digitalis purpurea commonly used in clinical medicine has never been an ideal therapeutic agent. The various preparations differ widely in composition and potency, and require biological standardization. Furthermore, the U.S.P. product may vary in strength with each revision. For instance, the digitalis in U.S.P. XI is approximately 30 per cent more potent than that in U.S.P. X, and the United States Pharmacopeia allows a 40 per
SOKOLOW M, CHAMBERLAIN FL. CLINICAL EVALUATION OF CEDILANID1. Ann Intern Med. ;18:204–213. doi: 10.7326/0003-4819-18-2-204
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Published: Ann Intern Med. 1943;18(2):204-213.
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