PHILIP D. MCMASTER, M.D.; ROBERT ELMAN, M.D.
Clinical interest in urobilin has always been great, yet at the present day the conclusions confidently drawn by workers with the substance far outrun actual knowledge of it. Analysis of the previous literature makes clear that the hypotheses of the origin of this pigment show no semblance of accord (1, 2). Every conceivable organ and tissue has been championed by one author or another as the sole site of origin of urobilin.
In the course of studies upon the physiology of bile made in this laboratory, methods were described (3, 4) whereby animals can be totally, partially and intermittently deprived
MCMASTER PD, ELMAN R. Urobilin Physiology and Pathology1. Ann Intern Med. ;1:68–73. doi: 10.7326/0003-4819-1-2-68
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Published: Ann Intern Med. 1927;1(2):68-73.
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