C. K. HSIEH, M.D.
The remarkable Graham method for visualization of gall bladder since its discovery in 1923 (1) is now widely used as a routine procedure in the Roentgen diagnosis of gall bladder conditions. The high toxicity of the tetrahalogenophenolphthaleins employed in this test is well known as evidenced by the reports of some marked constitutional reactions after the administration of the drug sometimes observed in the earlier days of the development of this method of diagnosis. With the improvement of technique of administration and of purer preparation of the salts, however, any untoward effect has been eliminated. The substitution for the tetrabromphenolphthalein
HSIEH CK. Effects of Sodium Tetraiodophenolphthalein On Some Vital Organs1. Ann Intern Med. 1927;1:96–107. doi: 10.7326/0003-4819-1-2-96
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Published: Ann Intern Med. 1927;1(2):96-107.
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