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Urobilinogen of the urine was estimated quantitatively by the method of Gerwen. Definite increases in urinary urobilinogen were found in cases of liver pathology. Increased values were also found in some cases of diabetes mellitus, most of which showed some suggestive evidence of an accompanying liver pathology. This was proven in two cases coming to autopsy, one of which showed cirrhosis and the other marked passive congestion of the liver. Increases were also found in some cases in which no definite evidence of liver pathology could be found. Active cases of pernicious anemia showed this finding. Cases of severe nephritis
Observations on Urobilinogen in Urine.. Ann Intern Med. ;1:847. doi: 10.7326/0003-4819-1-10-847_1
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Published: Ann Intern Med. 1928;1(10):847.
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