DAVIL P. BARR, M.D.
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Although the disease known as multiple myeloma has held a fascination for many observers, knowledge of its nature has progressed very slowly. During a period of more than seventy-five years, less than 200 authentic cases have been reported. It was recognized as early as 1848 when Henry Bence Jones saw with Sir James Watson a patient whose urine contained a strange protein which he described as the "hydrated deuteroxyd of albumin." Two years later, the clinical history of this same patient was detailed by McIntyre under the designation of mollities ossium. The association of multiple bone lesions with the unusual
BARR DP. Multiple Myeloma1. Ann Intern Med. 1928;1:884–889. doi: 10.7326/0003-4819-1-11-884
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Published: Ann Intern Med. 1928;1(11):884-889.
Hematology/Oncology, Multiple Myeloma.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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