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Whipple is convinced that a wrong assumption has seriously hampered the study of certain human anemias. Attention has been focussed upon hypothetical toxins which were supposed to destroy red cells in vivo and thus bring about the anemia. Because it can be demonstrated that a few types of anemia were due to toxic or parasitic destruction of red cells (septicemia, drugs, malaria) it has been assumed that all other forms of anemia must be due to some hemolytic toxin produced in the intestinal tract, kidneys, tumor growths, etc. This idea is given up with great difficulty. Pernicious anemia is the
Hemoglobin Construction within the Body as Influenced by Diet Factors. A Consideration of Anemia Problems.. Ann Intern Med. ;1:1067–1068. doi: 10.7326/0003-4819-1-12-1067
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Published: Ann Intern Med. 1928;1(12):1067-1068.
Hematology/Oncology, Red Cell Disorders.
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