ALLEN K. KRAUSE
This address starts with the premise that the term Pathogenesis, applied to tuberculosis, seeks to define a purely clinical concept. Modern medicine has made it plain that anatomical effects of tubercle bacilli quite commonly and, indeed, rather characteristically exist in the body without appreciable disturbance of the economy of the human organism. After bacilli are received, tuberculous foci form; they evolve and subside, they come and go, they reproduce and spread, they remain engrafted throughout a lifetime; meanwhile, if situated away from the surface of the body, they pursue their course entirely unknown to their possessor, and unfelt. If (let
KRAUSE AK. Factors in the Pathogenesis of Tuberculosis12: With a Preliminary Discussion of Activity. Ann Intern Med. ;2:21–55. doi: 10.7326/0003-4819-2-1-21
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Published: Ann Intern Med. 1928;2(1):21-55.
Infectious Disease, Mycobacterial Infections.
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