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Fifteen diabetic children have been treated systematically with synthalin for over a year, and it has, therefore, been possible to make a more accurate judgment as to the effect upon the carbohydrate tolerance of the peroral use of this anti-diabetic remedy and as to the toxic effect upon the child's organism of its protracted use. As these writers have previously emphasized, an effective synthalin therapy is possible only by correct dosage more than one and a half mg. of synthalin per kilogram body-weight must not be given; they advise one mg. per kilogram body weight. Higher dosages produced constantly bad
Zur Frage der toxischen Synthalin—Wirkung bei diabetischen Kinder.. Ann Intern Med. ;2:299–300. doi: 10.7326/0003-4819-2-3-299
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Published: Ann Intern Med. 1928;2(3):299-300.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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