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Rowland (Archives of Internal Medicine, November, 1928) makes an important contribution to our knowledge of xanthomatosis in the correlation of a group of cases described as defects in membranous bones, exophthalmos and diabetes insipidus (Christian's syndrome). He considers fourteen cases all occurring in early childhood, six of the patients being girls and eight boys. In ten of the cases the probable onset of the affection occurred during the second year of life, with one each in the third, fourth, sixth and seventh year. In all cases the onset was insidious and periodic, so that in most cases the disease was
Generalized Xanthomatosis. Ann Intern Med. ;2:689–691. doi: 10.7326/0003-4819-2-7-689
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Published: Ann Intern Med. 1929;2(7):689-691.
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