WARREN C. HUNTER, M.A., M.D.
In a previous paper I (1) have shown that a high degree of resistance to the injurious effects of uranium in the kidney can be experimentally produced. In a considerable number of rabbits it was found that 54 to 96 times the quantity of poison known to kill original renal tubular cells was insufficient to damage the regenerated epithelium in the same location. After administration of even the largest doses of uranium the metal was still excreted by the kidney and this together with the lack of histologic evidence of cell injury was considered to be proof of an acquired
HUNTER WC. Experimental Study of Acquired Resistance of the Rabbit's Renal Epithelium to Mercuric Chloride12. Ann Intern Med. 1929;2:796–806. doi: 10.7326/0003-4819-2-8-796
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Published: Ann Intern Med. 1929;2(8):796-806.
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