GEORGE R. MINOT, M.D., S.D., F.A.C.P.
Toward the close of the nineteenth century, as the sciences of bacteriology and immunology were becoming well established the dawn of knowledge arose concerning the enormous importance of small amounts of chemical substances for the maintenance of health. It is known today that abnormal amounts, or an improper balance, of highly potent active principles derived from glands of internal secretion, and of vitamins, of inorganic and other substances contained in food, can lead to many sorts of disorders. The secretions of the ductless glands together with materials derived from food must form with blood a suitable environment to bathe
MINOT GR. Some Fundamental Clinical Aspects of Deficiencies1. Ann Intern Med. 1929;3:216–229. doi: 10.7326/0003-4819-3-3-216
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Published: Ann Intern Med. 1929;3(3):216-229.
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