WILLIS S. LEMON, M.D.
With the phylogenetic development of a hemolymph system, the contact of respiration and circulation became complete. Throughout all the metamorphosis that bridges the gap between primitive organs and the complicated bodily systems of vertebrates, this relationship is maintained, and the mutual dependence of one on the other is strengthened almost in direct ratio to the multiplication of the necessities of complicated processes of life.
These ancient functions of respiration and circulation of blood are so vital and so fundamental a part of life that they are protected by a physiologic reserve far in excess of any requirement that could be
LEMON WS. A Study of the Effect of Chronic Pulmonary Diseases on the Volume and Composition of the Blood1. Ann Intern Med. ;3:430–446. doi: 10.7326/0003-4819-3-5-430
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Published: Ann Intern Med. 1929;3(5):430-446.
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