E. G. WAKEFIELD, M.D.; HARRY P. POWELSON, M.D.; CHARLES S. MCVICAR, M.D.
Neubauer has been foremost in the investigation of a sodium salt of dehydrocholeic acid that would stimulate the liver to increased formation of bile. Most investigators have shown this drug to be practically without toxic effects and that it markedly increases the flow of bile. Our investigation was undertaken to see if we could obtain results comparable to those reported by Neubauer, Rusznyâk and others.
Drugs that would increase flow of bile were sought by ancient medical investigators. The term cholagogue which was used to designate drugs that increase the flow of bile came into use between the time of
WAKEFIELD EG, POWELSON HP, MCVICAR CS. The Use of Sodium Salt of Dehydrocholeic Acid (Decholin) as a Choleretic1. Ann Intern Med. ;3:572–577. doi: 10.7326/0003-4819-3-6-572
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Published: Ann Intern Med. 1929;3(6):572-577.
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