E. G. WAKEFIELD, M.D.
It has been shown2,3,5,6,7 that during the critical periods and terminal stages of Addison's disease renal insufficiency may be manifested and is evidenced by the retention of urea and by inability of the kidney to excrete water and phenolsulphonephthalein. The amount of total solids in the urine also may be lessened.
The object of my study was to determine if the concentration of serum inorganic sulphates is increased in Addison's disease. Also, if serum inorganic sulphates were found to be increased I hoped to establish whether the increase is a constant feature of the disease or whether it occurs only
E. G. WAKEFIELD. Serum Inorganic Sulphates In Addison's Disease. Ann Intern Med. 1930;3:662–666. doi: 10.7326/0003-4819-3-7-662
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Published: Ann Intern Med. 1930;3(7):662-666.
Adrenal Disorders, Endocrine and Metabolism.
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