E. G. WAKEFIELD, M.D.; CARL H. GREENE, M.D.
The majority of tests for hepatic function in clinical use at the present time are concerned primarily with disturbances in the formation and excretion of bile.11 Disturbances in the metabolic activity of the liver, on the other hand, are much less readily demonstrated in cases of hepatic disease. Significant disturbances in the level of blood sugar that can be ascribed solely to hepatic insufficiency, are exceedingly rare. Our experience with both fructose and galactose tolerance tests has indicated that although positive tests occur with greater frequency in the presence of hepatic disease, yet so many other factors influence the response
WAKEFIELD EG, GREENE CH. The Lactic Acid Content of the Blood and the Partition of Inorganic Sulphate in the Serum of Patients With Hepatic Disease1. Ann Intern Med. ;3:793–799. doi: 10.7326/0003-4819-3-8-793
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Published: Ann Intern Med. 1930;3(8):793-799.
Gastroenterology/Hepatology, Liver Disease.
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