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Six years ago these investigators began the publication of a series of experiments which established a specific type of hemolytic streptococcus as the cause of scarlet fever. In these experiments it was shown that the scarlet fever streptococcus produces a potent soluble toxin which is responsible for the toxemia, nausea and rash, and that recovery from the disease with subsequent immunity depends on the production of an antitoxin. The conclusions as to the etiology, specific toxin and antitoxin of scarlet fever have been verified by numerous reports in this and other countries, particularly that done by Nicolle in the Pasteur
The Control of Scarlet Fever.. Ann Intern Med. 1930;3:869–871. doi: 10.7326/0003-4819-3-8-869
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Published: Ann Intern Med. 1930;3(8):869-871.
Infectious Disease, Streptococcal Infections.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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