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The sudden release of bile obtained by incising the gall bladder of a decerebrated or ether-anesthetized frog is almost invariably attended by an abrupt change in the rate and character of beating of the heart. The first event is a transient arrest of the entire heart lasting between 1 and 10 seconds, almost always followed by a sinus bradycardia lasting from one-half to ten minutes. Subsequently there is a return to the initial rate of beating, although in a few instances progressive slowing, leading to excessive dilation and permanent arrest, have been observed. Not infrequently the first event to be
Reflexes from the Gall bladder to the Heart.. Ann Intern Med. 1930;3:1165. doi: 10.7326/0003-4819-3-11-1165_1
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Published: Ann Intern Med. 1930;3(11):1165.
Biliary Disorders, Cardiology, Gastroenterology/Hepatology, Neurology.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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