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Babkin's summary is to the effect that the subcutaneous injection of histamine stimulates the secretion of gastric juice. The acidity of this juice is normal, but its digestive power and content of organic substances is lower than in juice obtained by sham-feeding. The supposition is that histamine activates chiefly the parietal cells of the gastric glands, producing the solution of hydrochloric acid, and in a much lesser degree the peptic and mucoid cells, which supply the juice with enzymes and organic substances. The histamine gastric secretion, therefore, represents largely one particular function of the gastric glands, and does not give
The Value of Histamine as a Test of Gastric Secretion From a Physiologic Point of View.. Ann Intern Med. ;4:332. doi: 10.7326/0003-4819-4-3-332
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Published: Ann Intern Med. 1930;4(3):332.
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