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Piersol sums up his discussion of hepatic functional tests as follows: From his experience with liver function tests, as applied to a considerable group of patients suffering from various disorders, the three most practical and useful tests clinically are ((1) the retention of the dye bromsulphthalein; (2) the estimation of the serum bilirubin, particularly, the determination of the icterus index; and (3) the occurrence of urobilinogen in the urine. The retention of bromsulphthalein is not an early indication of liver dysfunction. The degree of retention is a helpful indication of the extent of liver damage. When dye retention occurs other
The Clinical Value of Tests of Liver Function.. Ann Intern Med. 1930;4:507. doi: 10.7326/0003-4819-4-5-507_1
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Published: Ann Intern Med. 1930;4(5):507.
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