I. W. HELD; A. ALLEN GOLDBLOOM; JULIUS CHASNOFF
Since the epoch-making discovery of von Mering and Minkowski1 in 1889 that a lesion in the islands of Langerhans is responsible for diabetes mellitus and the much more recent discovery of Banting and Best2 that insulin has a favorable effect on this condition, the tendency to ascribe every case of glycosuria and hyperglycemia to either functional or pathologic changes in the islands of Langerhans has been pronounced. However, it is possible for these conditions to occur without involvement of the islands of Langerhans and we feel that when one encounters such a case of hyperglycemia or glycosuria of noninsular origin
HELD IW, GOLDBLOOM AA, CHASNOFF J. Extra-Insular (Central) Glycosuria With Hyperglycemia Following Epidemic Encephalitis. Ann Intern Med. 1931;4:897–908. doi: 10.7326/0003-4819-4-8-897
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Published: Ann Intern Med. 1931;4(8):897-908.
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