R. A. PHILLIPS, M. D.; D. F. ROBERTSON, M. D.; W. C. CORSON, M. D.; G. F. IRWIN, M.D.
It has of course been known since the work of Zizzozero and Wooldridge that the thrombocytes are a definite factor in aiding coagulation and with their increase it has been shown by Duke1 that the coagulation time of the blood is diminished. Gunn2 with the ultra-violet light produced an increase of thrombocytes in rabbits. "The increase varied from 40%-100% of the original normal but always amounted to at least twice that of the normal variation in the animal." It occurred to us in considering this latter work that this action might be due to the vitamin D affected on the
PHILLIPS RA, ROBERTSON DF, CORSON WC, IRWIN GF. The Effect of Irradiated Ergosterol on the Thrombocytes and the Coagulation of the Blood1. Ann Intern Med. ;4:1134–1143. doi: 10.7326/0003-4819-4-9-1134
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Published: Ann Intern Med. 1931;4(9):1134-1143.
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