CURTIS BRUEN, M.D.
The treatment of diabetes mellitus is a problem in quantitative chemistry.
In functioning the organism exacts a certain output of energy from the metabolism of foodstuffs. This caloric requirement is equal to the basal metabolism, plus a percentage increment for the specific dynamic action of food, and a percentage increment for activity over and above basal. In order to meet this requirement the several foodstuffs must be metabolized in such amounts as correspond to the dietary equation
C=4.1 CH+4.1 P+9.3 F (1)
in which C represents calories per day, CH, P and F, grams of carbohydrate, protein, and fat respectively,
BRUEN C. Method for Adjusting the Diet in Diabetes. Ann Intern Med. ;4:1206–1211. doi: 10.7326/0003-4819-4-9-1206
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Published: Ann Intern Med. 1931;4(9):1206-1211.
Cardiology, Coronary Risk Factors, Diabetes, Endocrine and Metabolism.
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