JOHN C. KRANTZ JR., Ph.D.; A. A. SILVER, M.D.; BERNARD J. HOFFMAN
In a previous communication to this journal, one of us (J.K.) (1) studied the metabolism of a certain sodium malate mixture when employed as a dietary substitute for sodium chloride. The mixture studied consisted of 85.5 per cent of disodium malate, 9 per cent of trisodium citrate, 5 per cent of triammonium citrate and 0.5 per cent of manganese bromide. In this work the administration of this mixture of salts in the form of a condiment was shown to influence the acid-base equilibrium of the urine in the direction of the alkaline side. The malic acid was apparently completely metabolized.
KRANTZ JC, SILVER AA, HOFFMAN BJ. The Effect of Sodium Malate Combinations Upon Gastric Acidity. Ann Intern Med. ;4:1441–1446. doi: 10.7326/0003-4819-4-11-1441
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Published: Ann Intern Med. 1931;4(11):1441-1446.
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