H. L. ALEXANDER, M.D.
The word "allergy" as used in these remarks, has to do solely with the clinical condition that is represented by the asthma-hay fevereczema group of cases. The conception of this type of allergy, as well as its rapid and extensive development during the past fifteen years, has been dependent largely on the skin test. The test consists of the introduction of extracts of foreign substances called "allergens" or "atopens," into the dermal cells. If there be antibodies present to the particular allergen applied to these cells, a reaction in the form of a wheal with a surrounding erythematous zone will
ALEXANDER HL. An Evaluation of the Skin Test in Allergy12. Ann Intern Med. ;5:52–56. doi: 10.7326/0003-4819-5-1-52
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Published: Ann Intern Med. 1931;5(1):52-56.
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