CYRUS C. STURGIS, M.D., F.A.C.P.; RAPHAEL ISAACS, M.D., F.A.C.P.
The possibility that a defect in the stomach may be related to the etiology of pernicious anemia has been recognized for many years. This belief has been based upon a number of clinical facts, some of which have been established and confirmed by numerous observers. The most significant evidence suggesting this etiological relationship is that every patient, probably without exception, has at least a functional impairment of the stomach mucosa as indicated by the inability to secrete hydrochloric acid. This fact becomes even more significant now that it is known that hydrochloric acid is not secreted under the powerful
STURGIS CC, ISAACS R. Clinical and Experimental Observations on the Treatment of Pernicious Anemia with Desiccated Stomach and with Liver Extract12. Ann Intern Med. ;5:131–158. doi: 10.7326/0003-4819-5-2-131
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Published: Ann Intern Med. 1931;5(2):131-158.
Gastroenterology/Hepatology, Hematology/Oncology, Red Cell Disorders.
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