DWIGHT L. WILBUR, M.D.; HOWARD R. HARTMAN, M.D., F.A.C.P.
Malignant melanoma, frequently termed melanosarcoma or melano-epithelioma, is one of the most malignant tumors encountered in man. In some instances, however, the body seems to possess unusual resistance to metastasis from these tumors and it may be years after the appearance or removal of the primary growth before sudden, rapid and overwhelming metastasis occurs. This type of growth should, therefore, lend itself well to the study of the mechanisms of metastasis of tumors and bodily resistance to tumor growth, were it possible, with present knowledge, to approach such a study. The established observations of the delay in metastasis of these
WILBUR DL, HARTMAN HR. Malignant Melanoma with Delayed Metastatic Growths1. Ann Intern Med. ;5:201–211. doi: 10.7326/0003-4819-5-2-201
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Published: Ann Intern Med. 1931;5(2):201-211.
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