ALVAN L. BARACH, M.D.
Oxygen is the fundamental requirement for the transformation of energy in the body. A normal supply of oxygen to the tissues in an individual living at sea level atmospheric pressure is maintained essentially by intact respiratory and cardiac systems. Although the metabolism is not altered by an increase in the oxygen supply (Voit,1 Pfluger,2 and Benedict and Higgins,3) reduction in the normal amount of oxygen furnished to the tissues results in profound alterations in the chemical processes of the body. A state of oxygen-want or anoxemia may be produced by a diminished concentration of oxygen in the outside air
BARACH AL. The Therapeutic Use of Oxygen in Heart Disease1. Ann Intern Med. ;5:428–440. doi: 10.7326/0003-4819-5-4-428
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Published: Ann Intern Med. 1931;5(4):428-440.
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