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From extensive experimentation with several strains of transplantable tumors, Lumsden believes that it may be safely concluded that anti-malignant-cell bodies, lethal to cancer cells but harmless to normal tissue cells, can be produced. When an implanted tumor already established in the body is gradually destroyed by injecting antiserum or formalin into it, active immunity against the tumor is induced by a mechanism which may be called autovaccination. It has still to be learned whether similar effects can be obtained with spontaneous tumors, in which the relationship between host tissue and invading tissue may be quite different.
Tumor Immunity.. Ann Intern Med. ;5:525. doi: 10.7326/0003-4819-5-4-525_3
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Published: Ann Intern Med. 1931;5(4):525.
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