MORRIS H. KAHN, M.A.,M.D., F.A.C.P.; LLOYD K. RIGGS, Ph.D.
The effects of propylene, an unsaturated hydrocarbon of the olefine series, as an anesthetic in animals have been reported in a number of communications by Halsey4,5,6 and his coworkers, by Riggs1,2,3 and Goulden3 and by others, with interesting and encouraging results. All have reported that propylene was an effective anesthetic in concentrations of 40 to 60 per cent by volume. None of these authors have reported either an immediate or delayed toxic action of this hydrocarbon. It appeared, therefore, that propylene might with safety be tried out in actual surgical practice.
A group of research workers in New Orleans under
KAHN MH, RIGGS LK. Electrocardiographic Studies of the Effects of Propylene as a General Anesthetic in Man1. Ann Intern Med. ;5:651–658. doi: 10.7326/0003-4819-5-5-651
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Published: Ann Intern Med. 1931;5(5):651-658.
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