WILLARD OWEN THOMPSON, M.D., F.A.C.P.; PHEBE K. THOMPSON, M.D.
Until about ten years ago, the treatment of exophthalmic goiter by iodine was considered a dangerous procedure, although it was not claimed that its immediate effects were always harmful. The attitude then prevalent is fairly well expressed in the statement of T. Kocher1 "Es ist ein zweischneidigen Schwert und der Schaden überwiegt" (it is a two-edged sword and harm predominates). Following the demonstration of the clinical improvement and the reduction in basal metabolism during its administration to patients with toxic goiter2, the pendulum swung almost completely to the other extreme. The consequence has been that most beneficial results that occur
THOMPSON WO, THOMPSON PK. Fallacies and Dangers in the Treatment of Exophthalmic Goiter by Iodine12. Ann Intern Med. ;5:1129–1137. doi: 10.7326/0003-4819-5-9-1129
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Published: Ann Intern Med. 1932;5(9):1129-1137.
Endocrine and Metabolism, Thyroid Disorders.
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